The Spanish letter E is pronounced more or less like "ay," as in say or may, but without the "y" sound at the end.
|e||the letter e|
Type of vowel
|Hard vs soft||E is a soft vowel|
|Strong vs weak||E is a strong vowel|
Please note that this explanation is only a guideline for the Spanish that I know, which is Castilian Spanish. There are many regional variations in Spanish pronunciation.